Ergothioneine

Ergothioneine is a sulfur-containing amino-acid derivative found in mushrooms. This page explains the compound, where it occurs in nature, and how FC Materials supplies it to manufacturers.

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What is ergothioneine?

Ergothioneine is a naturally occurring derivative of the amino acid histidine. Its ring carries a sulfur atom, which gives the molecule its distinctive chemistry. It is also a betaine, meaning its amino nitrogen carries three methyl groups.

The name comes from ergot, the fungus from which the compound was first isolated. Ergothioneine is often shortened to EGT in trade literature.

Where it occurs in nature

Fungi and certain bacteria make ergothioneine. Humans do not make it and take it in from food. Edible mushrooms are the best-known dietary source, and levels vary between species.

Commercial ergothioneine can be extracted from mushroom material or made by other routes. The route matters, because it shapes how a brand may describe the ingredient on pack.

How FC Materials supplies ergothioneine

FC Materials offers ergothioneine as GLISERA EGT®, a branded ingredient naturally extracted from golden oyster mushroom. FC does not manufacture it. FC sources it from a trusted global partner and helps with cost, quality and documentation. Full ingredient details are on the GLISERA EGT® branded page.

Formulation notes

  • The branded page describes the ingredient as a water-soluble powder. Drink and sachet formats are a natural first test.
  • For capsules and tablets, check flow, bulk density and compatibility with your excipients.
  • Mushroom extracts can carry colour and odour notes. Assess them in your base before scale-up.
  • Agree storage temperature and moisture limits with the supplier, then confirm with your own stability work.

What to ask your supplier

  • A batch certificate of analysis with the ergothioneine assay and the test method used.
  • The source of the ergothioneine: mushroom extraction or another production route.
  • The fungal material used, such as fruiting body or mycelium.
  • Results for heavy metals, pesticide residues and microbiology.
  • Allergen, GMO and vegan status statements.
  • A current specification sheet and safety data sheet.

Any claims on a finished product must meet the rules of each market where it is sold. For specification questions, WhatsApp us.